intermediate 1k

CC(C)(C)OC(=O)NC(=N)c1ccc(CNC(=O)[C@@H]2CCc3ncc(NCCc4ccccc4)c(=O)n32)cc1
Reaction #11053
intermediate 2a
수율 54.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CCN(CC)c1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OC(C)(C)C)cc1)CC2
Reaction #11054
intermediate 3a
수율 100.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CC(C)Nc1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OC(C)(C)C)cc1)CC2
Reaction #11055
intermediate 4a
수율 65.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CCNc1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OC(C)(C)C)cc1)CC2
Reaction #11056
intermediate 5a
수율 60.5%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CC(C)(C)OC(=O)NC(=N)c1ccc(CNC(=O)[C@@H]2CCc3ncc(NC4CCCC4)c(=O)n32)cc1
Reaction #11057
intermediate 6a
수율 57.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CC(C)CNc1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OC(C)(C)C)cc1)CC2
Reaction #11058
intermediate 7a
수율 79.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CCCNc1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OC(C)(C)C)cc1)CC2
Reaction #11059
intermediate 8a
수율 46.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CC(C)CN(CC(C)C)c1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OC(C)(C)C)cc1)CC2
Reaction #11060
intermediate 9a
수율 79.5%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CCC(CC)Nc1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OC(C)(C)C)cc1)CC2
Reaction #11061
intermediate 11a
수율 24.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C=CCN(C(=O)OCc1ccccc1)c1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OCc3ccccc3)cc1)C[C@@]2(C)NCC
Reaction #11084
26b
수율 54.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
C=CCN(C(=O)OCc1ccccc1)c1cnc2n(c1=O)[C@H](C(=O)NCc1ccc(C(=N)NC(=O)OCc3ccccc3)cc1)C[C@@]2(C)NC(C)C
Reaction #11085
27a
수율 28.1%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08