부분 구조 검색

751175

CCS(=O)(=O)c1ccc(NC(=O)CCCc2ccc(B(O)O)cc2)cc1CNC(=O)OC(C)(C)C
Reaction #183265
DOI: 10.1039/C8SC04228D
CCc1cc(C(Nc2cccc(C(N)=O)c2)C(=O)O)ccc1CCCC(=O)Nc1ccc(S(=O)(=O)C(C)C)c(CN(C)C(=O)OC(C)(C)C)c1
Reaction #750706
DOI: 10.1039/C8SC04228D
CCS(=O)(=O)c1ccc(NC(=O)CCCc2ccc(B(O)O)cc2)cc1CNC(=O)OC(C)(C)C
Reaction #822702
15C
수율 82.0%DOI: 10.6084/m9.figshare.5104873.v1
CCS(=O)(=O)c1ccc(NC(=O)CCCc2ccc(C(Nc3ccc(C#N)cc3)C(=O)O)cc2)cc1CNC(=O)OC(C)(C)C
Reaction #822703
2-(4-(4-(3-((tert-Butoxycarbonylamino)methyl)-4-(ethylsulfonyl)phenylamino)-4-oxobutyl)phenyl)-2-(4-cyanophenylamino)acetic acid
DOI: 10.6084/m9.figshare.5104873.v1
CCS(=O)(=O)c1ccc(NC(=O)CCCc2ccc(B(O)O)cc2)cc1CN(C)C(=O)OC(C)(C)C
Reaction #822714
17D
수율 76.0%DOI: 10.6084/m9.figshare.5104873.v1
CCS(=O)(=O)c1ccc(NC(=O)CCCc2ccc(C(Nc3ccc4c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nccc4c3)C(=O)O)cc2)cc1CN(C)C(=O)OC(C)(C)C
Reaction #822715
2-(1-(bis(tert-Butoxycarbonyl)amino)isoquinolin-6-ylamino)-2-(4-(4-(3-((tert-butoxycarbonyl(methyl)amino)methyl)-4-(ethylsulfonyl)phenylamino)-4-oxobutyl)phenyl)acetic acid
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)S(=O)(=O)c1ccc(NC(=O)CCCc2ccc(B(O)O)cc2)cc1CN(C)C(=O)OC(C)(C)C
Reaction #822718
18C
수율 80.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)S(=O)(=O)c1ccc(NC(=O)CCCc2ccc(C(Nc3ccc4c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nccc4c3)C(=O)O)cc2)cc1CN(C)C(=O)OC(C)(C)C
Reaction #822719
2-(1-(bis(tert-Butoxycarbonyl)amino)isoquinolin-6-ylamino)-2-(4-(4-(3-((tert-butoxycarbonyl(methyl)amino)methyl)-4-(isopropylsulfonyl)phenylamino)-4-oxobutyl)phenyl)acetic acid
DOI: 10.6084/m9.figshare.5104873.v1
CCc1cc(B(O)O)ccc1CCCC(=O)Nc1ccc(S(=O)(=O)C(C)C)c(CN(C)C(=O)OC(C)(C)C)c1
Reaction #822728
boronic acid
수율 67.0%DOI: 10.6084/m9.figshare.5104873.v1
CCc1cc(C(Nc2cccc(C(N)=O)c2)C(=O)O)ccc1CCCC(=O)Nc1ccc(S(=O)(=O)C(C)C)c(CN(C)C(=O)OC(C)(C)C)c1
Reaction #822729
2-(4-(4-(3-((tert-Butoxycarbonyl(methyl)amino)methyl)-4-(isopropylsulfonyl)phenylamino)-4-oxobutyl)-3-ethylphenyl)-2-(3-carbamoylphenylamino)acetic acid
DOI: 10.6084/m9.figshare.5104873.v1
CCc1cc(B(O)O)ccc1CCCC(=O)Nc1ccc(S(=O)(=O)C(C)C)c(CN(C)C(=O)OC(C)(C)C)c1
Reaction #895009
DOI: 10.1039/C8SC04228D
CCS(=O)(=O)c1ccc(NC(=O)CCCc2ccc(C(Nc3ccc(C#N)cc3)C(=O)O)cc2)cc1CNC(=O)OC(C)(C)C
Reaction #913891
DOI: 10.1039/C8SC04228D
CCS(=O)(=O)c1ccc(NC(=O)CCCc2ccc(C(Nc3ccc4c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nccc4c3)C(=O)O)cc2)cc1CN(C)C(=O)OC(C)(C)C
Reaction #1307100
DOI: 10.1039/C8SC04228D
CC(C)S(=O)(=O)c1ccc(NC(=O)CCCc2ccc(C(Nc3ccc4c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nccc4c3)C(=O)O)cc2)cc1CN(C)C(=O)OC(C)(C)C
Reaction #1321318
DOI: 10.1039/C8SC04228D