부분 구조 검색

444330

Cl.Cl.N[C@@H](CC(=O)N1CCn2cc(C(F)(F)F)nc2C1)Cc1cc(F)c(F)cc1F
Reaction #75869
title compound
수율 67.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F
Reaction #171331
7-[(3R)-3-[N-(tert-butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoyl]-3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F
Reaction #171336
7-[(3R)-3-[N-(tert-butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoyl]-3-(trifluoro-methyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine
DOI: 10.6084/m9.figshare.5104873.v1
CCOC(=O)c1ncn2c1CN(C(=O)CC(Cc1cc(F)c(F)cc1F)NC(=O)OC(C)(C)C)Cc1ccccc1-2
Reaction #182459
DOI: 10.1039/C8SC04228D
CC1CNC(=O)C(C)N(C(=O)CC(Cc2cc(F)c(F)cc2F)NC(=O)OC(C)(C)C)C1
Reaction #192829
DOI: 10.1039/C8SC04228D
CC1CCN(C(=O)CC(Cc2cc(F)c(F)cc2F)NC(=O)OC(C)(C)C)C(C)C(=O)N1
Reaction #200618
DOI: 10.1039/C8SC04228D
—
Reaction #220066
ethanol hexanes
수율 14.0%DOI: 10.6084/m9.figshare.5104873.v1
CCC1c2nccnc2CCN1C(=O)C[C@@H](Cc1cc(F)c(F)cc1F)NC(=O)OC(C)(C)C
Reaction #220067
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCn2nc(C(F)(F)F)nc2C1)Cc1cc(F)c(F)cc1F
Reaction #220245
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCn2nc(C(F)(F)F)nc2C1C(O)C1CC1)Cc1cc(F)c(F)cc1F
Reaction #220250
product
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCn2nc(C(F)(F)F)nc2C1CC1CC1)Cc1cc(F)c(F)cc1F
Reaction #220254
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCn2nc(C3CC3)nc2C1)Cc1cc(F)c(F)cc1F
Reaction #220257
title compound
DOI: 10.6084/m9.figshare.5104873.v1
CN(C)C(=O)CC1c2nc(C(F)(F)F)nn2CCN1C(=O)C[C@@H](Cc1cc(F)c(F)cc1F)NC(=O)OC(C)(C)C
Reaction #220264
7-[(3R)-3-[(tert-Butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoyl]-8-[2-(dimethylamino)-2-oxoethyl]-2-(trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-α]pyrazine
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)NC(CC(=O)N1CCn2c(cnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1F
Reaction #302060
DOI: 10.1039/C8SC04228D
CC(C)(C)OC(=O)N[C@@H](CC(=O)O)Cc1cc(F)c(F)cc1F
Reaction #308606
(R)-3-tert-butoxycarbonylamino-4-(2,4,5-trifluoro-phenyl)-butyric acid
DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #308609
R-[3-oxo-1-(2,4,5-trifluoro-benzyl)-3-(3-trifluoromethyl-5,6-dihydro-8H-imidazo[1,5-a]pyrazin-7-yl)-propyl]carbamic acid tert-butyl ester
수율 88.0%DOI: 10.6084/m9.figshare.5104873.v1
CC(=O)c1nc(C(F)(F)F)n2c1CN(C(=O)C[C@@H](Cc1cc(F)c(F)cc1F)NC(=O)OC(C)(C)C)CC2
Reaction #308665
(R)-[3-(1-acetyl-3-trifluoromethyl-5,6-dihydro-8H-imidazo[1,5-a]pyrazin-7-yl)-3-oxo-1-(2,4,5-trifluoro-benzyl)-propyl]-carbamic acid tert-butyl ester
DOI: 10.6084/m9.figshare.5104873.v1
CC(C)(C)OC(=O)N[C@@H](CC(=O)N1CCn2c(C(F)(F)F)nc(C(=O)C3CCCC3)c2C1)Cc1cc(F)c(F)cc1F
Reaction #308669
(R)-[3-(1-cyclopentanecarbonyl-3-trifluoromethyl-5,6-dihydro-8H-imidazo[1,5-a]pyrazin-7-yl)-3-oxo-1-(2,4,5-trifluoro-benzyl)-propyl]-carbamic acid tert-butyl ester
수율 72.0%DOI: 10.6084/m9.figshare.5104873.v1
COC(=O)c1nc(C(F)(F)F)n2c1[C@@H](C)N(C(=O)CC(Cc1cc(F)c(F)cc1F)NC(=O)OC(C)(C)C)CC2
Reaction #308691
(R)-7-[3-tert-butoxycarbonylamino-4-(2,4,5-trifluoro-phenyl)-butyryl]-8-methyl-3-trifluoromethyl-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine-1-carboxylic acid methyl ester
수율 77.2%DOI: 10.6084/m9.figshare.5104873.v1
—
Reaction #314427
N-BOC
DOI: 10.6084/m9.figshare.5104873.v1
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