유사 구조 검색

198643

Cc1nc(N)nc2c1C(=NOC(CCO)C(=O)N(C)C)NC(c1ccc(F)cc1Br)C2

Reaction #186806

DOI: 10.1039/C8SC04228D

Cc1nc(N)nc2c1C(=NOCCC1COC(C)(C)O1)NC(c1ccc(F)cc1Br)C2

Reaction #201535

DOI: 10.1039/C8SC04228D

Cc1nc(N)nc2c1C(=NOCC1COCCO1)NC(c1ccc(F)cc1Br)C2

Reaction #222072

DOI: 10.1039/C8SC04228D

Cc1nc(N)nc2c1C(=NOC1CCOC1=O)NC(c1ccc(F)cc1Br)C2

Reaction #272786

DOI: 10.1039/C8SC04228D

Cc1nc(N)nc2c1C(=NOCC1COC(C)(C)O1)NC(c1ccc(F)cc1Br)C2

Reaction #275852

DOI: 10.1039/C8SC04228D

COc1cccc(-c2cc(F)ccc2C2Cc3nc(N)nc(C)c3C(=NOCC3COC(C)(C)O3)N2)n1

Reaction #284426

DOI: 10.1039/C8SC04228D

Cc1nc(N)nc2c1/C(=N/OC[C@H]1COC(C)(C)O1)N[C@@H](c1ccc(F)cc1Br)C2

Reaction #743764

(R,Z)-2-amino-7-(2-bromo-4-fluorophenyl)-4-methyl-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-one O—((R)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl oxime

수율 30.0%DOI: 10.6084/m9.figshare.5104873.v1

CC(=O)C#N.O

Reaction #743765

수율 442.8%DOI: 10.6084/m9.figshare.5104873.v1

Cc1nc(N)nc2c1/C(=N/OCC[C@H]1COC(C)(C)O1)N[C@@H](c1ccc(F)cc1Br)C2

Reaction #743766

(R,Z)-2-amino-7-(2-bromo-4-fluorophenyl)-4-methyl-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-one O-2-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)ethyl oxime

수율 65.0%DOI: 10.6084/m9.figshare.5104873.v1

Cc1nc(N)nc2c1/C(=N/OC[C@H]1COCCO1)N[C@@H](c1ccc(F)cc1Br)C2

Reaction #743767

(R,Z)-2-amino-7-(2-bromo-4-fluorophenyl)-4-methyl-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-one O—((R)-1,4-dioxan-2-yl)methyl oxime

수율 319.3%DOI: 10.6084/m9.figshare.5104873.v1

$COC(=O)[C@H](CCO/N=C1\N[C@@H](c2ccc(F)cc2Br)Cc2nc(N)nc(C)c21)OC$

Reaction #743769

(S)-methyl 4-((Z)—((R)-2-amino-7-(2-bromo-4-fluorophenyl)-4-methyl-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-ylidene)aminooxy)-2-methoxybutanoate

수율 12.0%DOI: 10.6084/m9.figshare.5104873.v1

COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3/C(=N/OC[C@H]3OC[C@H](O)[C@@H]3O)N2)n1

Reaction #743770

수율 30.0%DOI: 10.6084/m9.figshare.5104873.v1

Cc1nc(N)nc2c1/C(=N/O[Si](C)(C)C(C)(C)C)N[C@@H](c1ccc(F)cc1Br)C2

Reaction #743779

(R,Z)-2-amino-7-(2-bromo-4-fluorophenyl)-4-methyl-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-one O-tert-butyldimethylsilyloxime

수율 80.0%DOI: 10.6084/m9.figshare.5104873.v1

Cc1nc(N)nc2c1/C(=N/OCCN1CCOCC1)N[C@@H](c1ccc(F)cc1Br)C2

Reaction #743782

(R,Z)-2-amino-7-(2-bromo-4-fluorophenyl)-4-methyl-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-one O-2-morpholinoethyl oxime

수율 100.0%DOI: 10.6084/m9.figshare.5104873.v1

COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3/C(=N/OCCN3CCOCC3)N2)n1

Reaction #743783

(R,Z)-2-amino-7-(4-fluoro-2-(6-methoxypyridin-2-yl)phenyl)-4-methyl-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-one O-2-morpholinoethyl oxime

수율 61.9%DOI: 10.6084/m9.figshare.5104873.v1

COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3/C(=N/OCC[C@H](O)C(N)=O)N2)n1

Reaction #743787

(S)-4-((Z)—((R)-2-amino-7-(4-fluoro-2-(6-methoxypyridin-2-yl)phenyl)-4-methyl-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-ylidene)aminooxy)-2-hydroxybutanamide

수율 22.7%DOI: 10.6084/m9.figshare.5104873.v1

Cc1nc(N)nc2c1/C(=N/O)N[C@@H](c1ccc(F)cc1Br)C2

Reaction #743789

(R,Z)-2-amino-7-(2-bromo-4-fluorophenyl)-4-methyl-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-one oxime

수율 70.3%DOI: 10.6084/m9.figshare.5104873.v1

Cc1nc(N)nc2c1/C(=N/OCC[C@H]1COC(C)(C)O1)N[C@@H](c1ccc(F)cc1Br)C2

Reaction #743790

(R,Z)-2-amino-7-(2-bromo-4-fluorophenyl)-4-methyl-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-one O-2-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)ethyl oxime

수율 63.1%DOI: 10.6084/m9.figshare.5104873.v1

COc1cccc(-c2cc(F)ccc2[C@H]2Cc3nc(N)nc(C)c3/C(=N/O)N2)n1

Reaction #743791

(R,Z)-2-amino-7-(4-fluoro-2-(6-methoxypyridin-2-yl)phenyl)-4-methyl-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-one oxime

DOI: 10.6084/m9.figshare.5104873.v1

$COC(=O)[C@H](CCO/N=C1\N[C@@H](c2ccc(F)cc2-c2cccc(OC)n2)Cc2nc(N)nc(C)c21)O[Si](C)(C)C(C)(C)C$

Reaction #743799

(S)-methyl 4-((Z)—((R)-2-amino-7-(4-fluoro-2-(6-methoxypyridin-2-yl)phenyl)-4-methyl-7,8-dihydropyrido[4,3-d]pyrimidin-5(6H)-ylidene)aminooxy)-2-(tert-butyldimethylsilyloxy)butanoate

DOI: 10.6084/m9.figshare.5104873.v1

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