#1122

CNC(=O)c1ccccc1Nc1cc(Nc2cn(C)nc2C)ncc1C#N

수율 50.0%750 AstraZeneca ELN dataset

Cc1nn(C)cc1Nc1cc(Nc2cccc3c2C(=O)N(C)CC3)c(C#N)cn1

수율 7.3%750 AstraZeneca ELN dataset

Cc1nn(C)cc1Nc1cc(Nc2cccc3c2C(=O)N(C)CC3)c(C#N)cn1

수율 54.9%750 AstraZeneca ELN dataset

Cc1nn(C)cc1Nc1cc(Nc2cccc3c2C(=O)N(C)CC3)c(C#N)cn1

수율 43.8%750 AstraZeneca ELN dataset

Cc1nn(C)cc1Nc1cc(Nc2cccc3c2C(=O)N(C)CC3)c(C#N)cn1

수율 15.6%750 AstraZeneca ELN dataset

CONC(=O)c1ccccc1Nc1cc(Nc2cn(C)nc2C)ncc1Cl

수율 14.3%750 AstraZeneca ELN dataset

CNC(=O)c1ccccc1Nc1cc(Nc2cn(C)nc2C)ncc1Cl

수율 53.3%750 AstraZeneca ELN dataset

CONC(=O)c1ccccc1Nc1cc(Nc2cn(C)nc2C)ncc1C(F)(F)F

수율 11.2%750 AstraZeneca ELN dataset

CNC(=O)c1ccccc1Nc1cc(Nc2cn(C)nc2C)ncc1C(F)(F)F

수율 33.7%750 AstraZeneca ELN dataset

CONC(=O)c1ccccc1Nc1cc(Nc2cn(C)nc2C)ncc1Cl

Reaction #90782

desired product

수율 18.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_09

CNC(=O)c1cc(F)ccc1Nc1cc(Nc2cn(C)nc2C)ncc1Cl

Reaction #198975

DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (2/10)

CC(=O)Nc1cn(C)nc1C

Reaction #407335

DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (8/10)

Cc1nn(C)cc1Nc1c([N+](=O)[O-])cnc2ccc(Br)cc12

Reaction #532721

DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_07

Cc1nn(C)cc1Nc1cnc2c(n1)c(C(=O)NC(C)(C)C)cn2COCC[Si](C)(C)C

Reaction #610186

N-tert-butyl-2-(1,3-dimethyl-1H-pyrazol-4-ylamino)-5-((2-(trimethylsilyl)ethoxy)methyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide

수율 55.3%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_05

Cc1nn(C)cc1Nc1ncc(Cl)c(CCc2ccccc2C2(C(N)=O)CC2)n1

Reaction #679587

title compound 26

수율 25.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_01

CCOC(=O)c1cnc2ccc(-c3ccc(OC)c(OC)c3)nc2c1Nc1cn(C)nc1C

Reaction #775469

DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (3/10)

COc1cc(OCc2ccccc2)ccc1CC(=O)Nc1cn(C)nc1C

Reaction #1096939

N-(1,3-dimethylpyrazol-4-yl)-2-(4-benzyloxy-2-methoxyphenyl)acetamide

DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2011_07

CNC(=O)c1cc(F)ccc1Nc1cc(Nc2cn(C)nc2C)ncc1Cl

Reaction #1133115

2-(5-chloro-2-(1,3-dimethyl-1H-pyrazol-4-ylamino)pyridin-4-ylamino)-5-fluoro-N-methylbenzamide

DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_10

CNC(=O)c1ccc(F)cc1Nc1cc(Nc2cn(C)nc2C)ncc1Cl

Reaction #1133116

2-(5-chloro-2-(1,3-dimethyl-1H-pyrazol-4-ylamino)pyridin-4-ylamino)-4-fluoro-N-methylbenzamide

DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_10

CNC(=O)c1ccc(F)cc1Nc1cc(Nc2cn(C)nc2C)ncc1Cl

Reaction #1233892

DOI: 10.1039/C8SC04228DTraining data from https://doi.org/10.1039/C8SC04228D (7/10)

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