反応 #992700

反応方程式

3-methyl-N-(1-methylethyl)-2-nitrobenzeneacetamide

title product

3-methyl-N-(1-methylethyl)-2-nitrobenzeneacetamide

→

title compound

2-amino-3-methyl-N-(1-methylethyl)benzeneacetamide

溶媒

ethanol

反応条件

後処理

1. 1
   その他was placed under a balloon of nitrogen overnight
2. 2
   ろ過Then the reaction mixture was filtered through Celite® diatomaceous filter aid
3. 3
   その他The solvent was removed with a rotary evaporator

実験手順

To 3-methyl-N-(1-methylethyl)-2-nitrobenzeneacetamide (i.e. the title product of Step A) (0.40 g, 1.7 mmol) and 10% palladium on carbon (0.13 g) was added 20 mL of ethanol. The reaction mixture was placed under a balloon of nitrogen overnight. Then the reaction mixture was filtered through Celite® diatomaceous filter aid. The solvent was removed with a rotary evaporator to afford the title compound as a tan solid (0.29 g).

出典