反応 #9815

反応方程式

6-Nitro-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide

hydrogen

→

title compound

収率 46.4%

6-Amino-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide

収率 46.4%

溶媒

THF

MeOH

反応条件

後処理

1. 1
   ろ過The catalyst was filtered off
2. 2
   その他the filtrate evaporated
3. 3
   その他the residue chromatographed on silica

実験手順

0.917 g 6-Nitro-2,3-dihydro-benzo[1,4]oxathiine-4,4-dioxide (from g)) were hydrogenated in a mixture of 20 ml THF and 20 ml MeOH with 0.90 g 5% Pd—C at atmospheric hydrogen pressure for 90 min. at room temperature. The catalyst was filtered off, the filtrate evaporated and the residue chromatographed on silica to yield 370 mg of the title compound.

出典