反応 #981374

反応方程式

6,11-dihydro-11-oxodibenz[b,e]oxepin-2-carboxylic acid

thionyl chloride

→

title product

2-Chlorocarbonyl-6,11-dihydro-11-oxodibenz[b,e]oxepin

反応条件

後処理

1. 1
   温度Heat a solution of 5 gm
2. 2
   その他Evaporate the reaction mixture under vacuum to dryness
3. 3
   その他Repeat the evaporation with two 30 ml
4. 4
   その他Crystallize the residue from diisopropyl ether

実験手順

Heat a solution of 5 gm. of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-carboxylic acid and 40 ml. of thionyl chloride under reflux for 20 minutes. Evaporate the reaction mixture under vacuum to dryness. Repeat the evaporation with two 30 ml. portions of carbon tetrachloride. Crystallize the residue from diisopropyl ether to obtain the title product.

出典