反応 #979672

ord-534cb607f215431385d8a7d70f112e74

反応方程式

COC(=O)c1ccc2c(c1)/C(=C/CCl)c1ccccc1CO2
Compound h
COC(=O)c1ccc2c(c1)/C(=C/CCl)c1ccccc1CO2
methyl (E)-11-(2-chloroethylidene)-6,11-dihydrodibenz[b,e]oxepin-2-carboxylate
Oc1nc2ccccc2[nH]1
2-hydroxybenzimidazole
→
COC(=O)c1ccc2c(c1)/C(=C/Cn1c(O)nc3ccccc31)c1ccccc1CO2
objective compound
COC(=O)c1ccc2c(c1)/C(=C/Cn1c(O)nc3ccccc31)c1ccccc1CO2
Methyl (E)-11-[2-(2-hydroxy-1-benzimidazolyl)ethylidene]-6,11-dihydrodibenz[b,e]oxepin-2-carboxylate

反応物

COC(=O)c1ccc2c(c1)/C(=C/CCl)c1ccccc1CO2
Compound h
COC(=O)c1ccc2c(c1)/C(=C/CCl)c1ccccc1CO2
methyl (E)-11-(2-chloroethylidene)-6,11-dihydrodibenz[b,e]oxepin-2-carboxylate
Oc1nc2ccccc2[nH]1
2-hydroxybenzimidazole

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

Compound h, 2.0 g and 4.3 g of 2-hydroxybenzimidazole were treated in a manner similar to Example 173 to give 0.3 g of the objective compound.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US05118701uspto-grants-1992_06