反応 #975231

反応方程式

4-(chloromethyl)benzoic acid

isopropanol

→

benzoate

Isopropyl 4-(chloromethyl)benzoate

反応条件

後処理

1. 1
   その他Isopropyl 4-(chloromethyl)benzoate 13d was prepared

実験手順

Isopropyl 4-(chloromethyl)benzoate 13d was prepared by reacting 4-(chloromethyl)benzoic acid 24 with isopropanol according to the procedure described for the compound 13a in Example 16 (scheme 7). The benzoate 13d was isolated as colorless oil in 89% yield (1.90 g). 1H NMR (400 MHz, CDCl3): δ 1.35 (6H, m); 4.59 (2H, s); 5.25 (2H, m); 7.42 (1H, m); 7.44 (1H, broad s); 8.00 (1H, broad s); 8.02 (1H, s).

出典