反応 #9748

ord-eac842baaa6b4a0a9a150ca3464ed4ce

反応方程式

COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]
intermediate 62
COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]
({3-(Methoxycarbonyl)-5-[4-(trifluoromethyl)phenyl]-2-furyl}methyl)(triphenyl)phosphonium bromide
CC(C)=O
propanone
→
CC(C)Cc1oc(-c2ccc(C(F)(F)F)cc2)cc1CO
{2-isobutyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}methanol

反応物

COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]
intermediate 62
COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]
({3-(Methoxycarbonyl)-5-[4-(trifluoromethyl)phenyl]-2-furyl}methyl)(triphenyl)phosphonium bromide
CC(C)=O
propanone

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

Prepared from intermediate 62 and propanone

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US07091237B2uspto-grants-2006_08