反応 #9747

ord-04cb01da013e4d209aa3a8604394347d

反応方程式

COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]
intermediate 62
COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]
({3-(Methoxycarbonyl)-5-[4-(trifluoromethyl)phenyl]-2-furyl}methyl)(triphenyl)phosphonium bromide
CC(C)C=O
2-methylpropanal
→
CC(C)CCc1oc(-c2ccc(C(F)(F)F)cc2)cc1CO
{2-isopentyl-5-[4-(trifluoromethyl)phenyl]-3-furyl}methanol

反応物

COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]
intermediate 62
COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]
({3-(Methoxycarbonyl)-5-[4-(trifluoromethyl)phenyl]-2-furyl}methyl)(triphenyl)phosphonium bromide
CC(C)C=O
2-methylpropanal

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

Prepared from intermediate 62 and 2-methylpropanal

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US07091237B2uspto-grants-2006_08