反応 #969897

反応方程式

Dimethylformamide

2-amino-5-methoxybenzenesulphonic acid

thionyl chloride

→

title product

N-[[[2-(chlorosulphonyl)-4-methoxyphenyl]amino]methylene]-N-methyl-methanaminium chloride

溶媒

toluene

反応条件

後処理

1. 1
   温度is maintained at that temperature for 1.5 hours
2. 2
   温度After cooling
3. 3
   その他the stirred reaction solution
4. 4
   その他A precipitate is formed which
5. 5
   ろ過is rapidly filtered off
6. 6
   洗浄rinsed with toluene
7. 7
   乾燥dried at 40° C. in vacuo in the presence of KOH pellets

実験手順

Dimethylformamide (0.152 mol) is added dropwise to a suspension of 2-amino-5-methoxybenzenesulphonic acid (0.152 mol) in thionyl chloride (0.763 mol). The reaction mixture is heated very gradually to 70° C. and is maintained at that temperature for 1.5 hours. After cooling, the stirred reaction solution is treated by the addition of 20 ml of toluene. A precipitate is formed which is rapidly filtered off, rinsed with toluene and then dried at 40° C. in vacuo in the presence of KOH pellets, to yield the title product.

出典