反応 #960525

反応方程式

3′-Fluoro-3,4′-dinitrobiphenyl-4-amine

K2CO3

MeNH2

→

product

収率 100.0%

N3-Methyl-3′,4-dinitrobiphenyl-3,4′-diamine

収率 100.0%

溶媒

DCM

反応条件

後処理

1. 1
   洗浄The solution was then washed with H2O and brine
2. 2
   乾燥The organic layer was dried (MgSO4)
3. 3
   ろ過filtered
4. 4
   濃縮concentrated in vacuo

実験手順

3′-Fluoro-3,4′-dinitrobiphenyl-4-amine (285 mg, 1.03 mmol) was suspended in DCM (10 mL). K2CO3 (284 mg, 2.06 mmol) was added, followed by MeNH2 (40% in H2O, 10 mL). The mixture was stirred at room temperature for 72 h. The solution was then washed with H2O and brine. The organic layer was dried (MgSO4), filtered and concentrated in vacuo to afford the product as a red solid (296 mg, 100%).

出典