反応 #96031

反応方程式

4-(4-chloro-3-dimethylsulfamoylphenyl)-2-(2-chlorophenyl-imino)-3-methylthiazolidin-4-ol hydrobromide

water

→

4-(4-Chloro-3-dimethylsulfamoylphenyl)-2-(2-chlorophenylimino)-3-methyl-4-thiazoline

溶媒

methanol

triethylamine

反応条件

後処理

1. 1
   ろ過the crystals are filtered off
2. 2
   その他recrystallized from ethanol

実験手順

10.8 g of 4-(4-chloro-3-dimethylsulfamoylphenyl)-2-(2-chlorophenyl-imino)-3-methylthiazolidin-4-ol hydrobromide are heated at the boil in a mixture of 100 ml of methanol and 10 ml of triethylamine for 30 minutes and the reaction mixture is then poured into an equal volume of water. The resulting mixture is stirred for about 2 hours at room temperature and the crystals are filtered off and recrystallized from ethanol. Melting point 153°-156° C.

出典