反応 #96024

ord-2c83853343d54aa4bb66be59f786f2ba

反応方程式

CN1C(=Nc2ccccc2)SCC1(O)c1ccc(Cl)c(S(=O)(=O)N(C)C)c1
4-(4-chloro-3-dimethylsulfamoylphenyl)-3-methyl-2-phenyliminothiazolidin-4-ol
→
CN(C)S(=O)(=O)c1cc(-c2csc(=Nc3ccccc3)n2C)ccc1Cl
4-(4-Chloro-3-dimethylsulfamoylphenyl)-3-methyl-2-phenylimino-4-thiazoline

反応物

CN1C(=Nc2ccccc2)SCC1(O)c1ccc(Cl)c(S(=O)(=O)N(C)C)c1
4-(4-chloro-3-dimethylsulfamoylphenyl)-3-methyl-2-phenyliminothiazolidin-4-ol

試薬

なし

溶媒

CC(=O)O
acetic acid

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    workup.DISTILLATIONthe solvent is distilled off
  2. 2
    その他to crystallize

実験手順

8.52 g (0.02 mole) of 4-(4-chloro-3-dimethylsulfamoylphenyl)-3-methyl-2-phenyliminothiazolidin-4-ol in 100 ml of glacial acetic acid are heated at the boil for 3 hours, the solvent is distilled off and the residue is made to crystallize using water. Melting point 180° C.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US04346088uspto-grants-1982_08