反応 #955921

ord-a615ba1b682243c6b46e338c458eba06

反応方程式

CCc1ccc(C(=O)OC)c(C)c1
Methyl 4-ethyl-2-methylbenzoate
CCc1ccc(C(=O)O)c(C)c1
title product
CCc1ccc(C(=O)O)c(C)c1
4-Ethyl-2-methylbenzoic acid

試薬

なし

溶媒

反応条件

温度
60°CELSIUS
詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    洗浄The mixture was washed with hexanes

実験手順

Methyl 4-ethyl-2-methylbenzoate (example 10c) (2.37 g) was dissolved in aq. NaOH (1M, 40 mL) and the solution heated at 60° C. overnight. The mixture was washed with hexanes and the aqueous layer was acidified with 6N HCl to pH 2. The title product was obtained as a white precipitate, following filtration and drying (2.17 g, 80%).

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US08968708B2uspto-grants-2015_03