反応 #955904

反応方程式

nitric acid

1-(1′-hydroxyoctadecyloxy)-2,3-dioctadecyloxybenzene

→

3-(1′-hydroxyoctadecyloxy)-4,5-dioctadecyloxy nitrobenzene

収率 76.2%

溶媒

dichloromethane

dichloromethane

反応条件

後処理

1. 1
   workup.ADDITIONDispersed
2. 2
   workup.ADDITIONwas added
3. 3
   workup.ADDITIONInto the resulting dispersion, added
4. 4
   ろ過silica gel was filtered off
5. 5
   濃縮After the filtrate was concentrated under reduced pressure, 300 ml of methanol
6. 6
   workup.ADDITIONwas added
7. 7
   workup.STIRRINGstirred
8. 8
   その他Resulting precipitant
9. 9
   ろ過was filtered off

実験手順

Dispersed was 63 g of silica gel into 21 g of nitric acid and 150 ml of dichloromethane was added. Into the resulting dispersion, added was a solution dissolving 5.0 g of 1-(1′-hydroxyoctadecyloxy)-2,3-dioctadecyloxybenzene in 30 ml of dichloromethane. After stirring for 15 minutes, silica gel was filtered off. After the filtrate was concentrated under reduced pressure, 300 ml of methanol was added and stirred. Resulting precipitant was filtered off to obtain 4.0 g of 3-(1′-hydroxyoctadecyloxy)-4,5-dioctadecyloxy nitrobenzene (yield: 76%).

出典