反応 #95558

反応方程式

Potassium tertiary butoxide

4-dichloromethyl-6,6-dimethyl-3-oxabicyclo[3.1.0]-hexan-2-one

hydrochloric acid

→

cis 2-(2,2-dichlorovinyl)-3,3-dimethylcyclopropane carboxylic acid

溶媒

dimethylsulphoxide

water

反応条件

後処理

1. 1
   抽出extracted CDCl3

実験手順

Potassium tertiary butoxide (0.45 mol) was added to a solution of 4-dichloromethyl-6,6-dimethyl-3-oxabicyclo[3.1.0]-hexan-2-one (0.16 mmol) in dry dimethylsulphoxide (0.4 ml) and stirred at room temperature for 1/2 hour. The solution was then diluted with water, acidified with concentrated hydrochloric acid and extracted CDCl3. NMR analysis showed a virtually quantitative yield of the desired cis acid.

出典