反応 #95386

反応方程式

2,6-bis-(chloroacetyl-amino)benzo[1,2-d:5,4-d']bisthiazole

2-ethyl-piperidine

→

compounds ( a )

収率 47.0%

2,6-Bis-(2-ethylpiperidino-acetylamino)-benzo[1,2-d:5,4-d']bisthiazole

収率 47.0%

( b )

収率 37.0%

2-Amino-6-(2-ethylpiperidino-acetylamino)-benzo[1,2-d:5,4-d']bisthiazole

収率 37.0%

溶媒

dioxane

反応条件

後処理

1. 1
   温度was refluxed for 2 hours

実験手順

A mixture of 8.0 gm of 2,6-bis-(chloroacetyl-amino)benzo[1,2-d:5,4-d']bisthiazole, 10.0 gm of 2-ethyl-piperidine and 100 ml of dioxane was refluxed for 2 hours. The reaction mixture was worked up as described in Example 16; the compounds (a) (47% of theory, from ethanol), M.P. 201°-203° C., and (b) (37% of theory, from ethanol), M.P. 223°-225° C. were isolated.

出典