反応 #95379

反応方程式

2,6-diamino-benzo[1,2-d:5,4-d']bisthiazole

p-nitro-phenyl chloroacetate

→

2,6-bis-(chloroacetyl-amino)-benzo[1,2-d:5,4-d']bisthiazole

収率 93.0%

溶媒

dioxane

反応条件

後処理

1. 1
   温度were refluxed for 15 minutes
2. 2
   温度to cool
3. 3
   その他the crystalline substance which had separated out
4. 4
   ろ過was filtered off
5. 5
   洗浄washed
6. 6
   その他dried

実験手順

A mixture consisting of 222 mgm of 2,6-diamino-benzo[1,2-d:5,4-d']bisthiazole, 500 mgm of p-nitro-phenyl chloroacetate and 5 ml of dioxane were refluxed for 15 minutes. The reaction mixture was allowed to cool, and the crystalline substance which had separated out was filtered off, washed and dried. 350 mgm (93% of theory) of 2,6-bis-(chloroacetyl-amino)-benzo[1,2-d:5,4-d']bisthiazole, M.P. 330° C., were obtained.

出典