反応 #95310

反応方程式

N-(2-cyanoethyl)-3-methylaniline

chloroformic acid-3-(trichloromethylcarbonylamino)-phenyl ester

→

N-(2-cyanoethyl)-3-methylcarbanilic acid-[3-(trichloromethylcarbonylamino)-phenyl]-ester

溶媒

acetonitrile

—

ice water

acetonitrile

反応条件

後処理

1. 1
   workup.ADDITIONis added dropwise
2. 2
   温度The reaction mixture is heated
3. 3
   温度cooled
4. 4
   ろ過the precipitate filtered
5. 5
   その他recrystallized from isopropanol

実験手順

Into a solution of 16.0 g N-(2-cyanoethyl)-3-methylaniline in 100 ml acetonitrile, 31.7 g chloroformic acid-3-(trichloromethylcarbonylamino)-phenyl ester taken up in 100 ml acetonitrile is added dropwise. The reaction mixture is heated to boiling for another 10 minutes, cooled, stirred in 500 ml ice water, the precipitate filtered and recrystallized from isopropanol.

出典