反応 #94989

反応方程式

betaphenylethyl alcohol

cyclohexanol

sulfuric acid

→

CYCLOHEXYL PHENETHYLETHER

反応条件

後処理

1. 1
   その他Into a 2 liter reaction vessel
2. 2
   その他equipped with stirrer
3. 3
   温度thermometer, heating mantle and overhead condenser with azeotrope takeoff apparatus
4. 4
   温度maintained at a temperature in the range of 104°-127° C.
5. 5
   温度at reflux
6. 6
   その他while azeotropically removing 80 ml water
7. 7
   その他At the end of the 3 hour period
8. 8
   その他180° C.

実験手順

Into a 2 liter reaction vessel equipped with stirrer, thermometer, heating mantle and overhead condenser with azeotrope takeoff apparatus is placed 488 grams of betaphenylethyl alcohol; 440 grams of cyclohexanol and 100 grams of concentrated sulfuric acid. The reaction mass is then heated to a temperature of 115° C. and maintained at a temperature in the range of 104°-127° C. at reflux while azeotropically removing 80 ml water, for a period of 3 hours. At the end of the 3 hour period, a sample is analyzed by means of GLC analysis (conditions: 180° C. isothermal using an SE-30 packed column). FIG. 1A is the GLC profile of the reaction product at this point.

出典