反応 #94760

反応方程式

[S]-1-[3-(5-chloro-2-thenoyl)-2-methylpropionyl]-L-proline

sodium thioacetate

→

1-[3-Acetylthio-3-(5-chloro-2-thenoyl)-2-methylpropionyl]-L-proline

溶媒

acetonitrile

反応条件

後処理

1. 1
   その他gives

実験手順

Bromination of the [S]-1-[3-(5-chloro-2-thenoyl)-2-methylpropionyl]-L-proline and reaction of the brominated product with sodium thioacetate in acetonitrile gives a mixture of the [R-(R*,S*)] and [R-(R*,R*)] isomers of the product of the Example as a glass.

出典