反応 #94654

ord-88a5771ce22f40a5abf41833950d2c01

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    温度was heated on a steam bath for 21/4 hours
  2. 2
    温度It was cooled
  3. 3
    その他The resulting precipitate was collected on a filter
  4. 4
    洗浄washed with a minimum of water
  5. 5
    その他recrystallized from water

実験手順

To a cold solution of 35 ml. of fuming sulfuric acid and 45 ml. of fuming nitric acid was added 35 grams of the 4-hydroxypyridine nitrate. After allowing the mixture to warm to room temperature over night it was heated on a steam bath for 21/4 hours. It was cooled and poured onto 500 grams of ice. The resulting precipitate was collected on a filter, washed with a minimum of water and recrystallized from water to give 3-nitro-4-pyridone, m.p. 282-284° C.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US04131677uspto-grants-1978_12