反応 #94568

反応方程式

methyl o-chlorophenylacetate

N-bromosuccinimide

→

methyl α-bromo-o-chlorophenylacetate

溶媒

carbon tetrachloride

反応条件

後処理

1. 1
   温度is refluxed for 20 hours
2. 2
   ろ過filtered through magnesium silicate
3. 3
   その他Evaporation under reduced pressure

実験手順

A stirred mixture of 36.9 g of methyl o-chlorophenylacetate, 36.0 g of N-bromosuccinimide, and 2 drops of 48% hydrobromic acid in 500 ml of carbon tetrachloride is refluxed for 20 hours and then filtered through magnesium silicate. Evaporation under reduced pressure gives methyl α-bromo-o-chlorophenylacetate as a straw-colored liquid.

出典