反応 #9455

反応方程式

Triethyl orthoformate

Meldrum's acid

biphenyl-3-ylamine

→

5-(biphenyl-3-ylaminomethylene)-2,2-dimethyl-[1,3]dioxane-4,6-dione

収率 95.5%

反応条件

後処理

1. 1
   workup.ADDITIONtreated

実験手順

Triethyl orthoformate (148 g, 1.00 mol), Meldrum's acid (137 g, 0.95 mol), and biphenyl-3-ylamine (155 g, 0.916 mol) were combined and treated according to the general procedure described in Part A of Example 1 to obtain 283 g of 5-(biphenyl-3-ylaminomethylene)-2,2-dimethyl-[1,3]dioxane-4,6-dione as a yellow solid.

出典