反応 #94547

反応方程式

Tri-n-butyl phosphine

monochloroacetic acid

phosphine

→

Tri-n-butyl(carboxymethyl)phosphonium Chloride

溶媒

methanol

反応条件

後処理

1. 1
   その他did not exceed about 30° C
2. 2
   その他The methanol solvent was subsequently evaporated under reduced pressure
3. 3
   その他leaving a colorless viscous liquid whose infrared spectrum and elemental analysis

実験手順

Tri-n-butyl phosphine (4.04 g, 0.02 mole) was added dropwise to a rapidly stirred solution of monochloroacetic acid (1.85 g, 0.02 mole) and 3.2 ml of methanol. The addition of the phosphine was at a rate such that the reaction temperature did not exceed about 30° C. The methanol solvent was subsequently evaporated under reduced pressure leaving a colorless viscous liquid whose infrared spectrum and elemental analysis corresponded to a compound of the formula

出典