反応 #94215

反応方程式

6-benzylsulfamoyl-5-chloro-1-indanone

bromine

→

6-Benzylsulfamoyl-2-bromo-5-chloro-1-indanone

溶媒

acetic acid

反応条件

後処理

1. 1
   その他yield the substance
2. 2
   その他of from 159° to 161° C. which
3. 3
   その他after reprecipitation
4. 4
   workup.ADDITIONfrom a mixture of ethyl acetate and petroleum ether
5. 5
   その他of from 176° to 178° C.

実験手順

According to Example 1 e), 10.05 g (30 mmoles) of 6-benzylsulfamoyl-5-chloro-1-indanone and 4.8 g (30 mmoles) of bromine in a total of 110 ml of glacial acetic acid yield the substance having a melting point of from 159° to 161° C. which after reprecipitation from a mixture of ethyl acetate and petroleum ether has a melting point in the range of from 176° to 178° C.

出典