反応 #94107

反応方程式

salicylaldehyde

hexamethylenediamine

→

N,N'-Bis-(2-hydroxybenzyl)-hexamethylenediamine

溶媒

isopropanol

反応条件

後処理

1. 1
   その他The product crystallises out at room temperature
2. 2
   workup.DISSOLUTIONis dissolved
3. 3
   workup.ADDITIONby boiling with the addition of a further 650 ml of isopropanol
4. 4
   ろ過The catalyst is filtered off
5. 5
   その他N,N'-bis-(2-hydroxybenzyl)hexamethylenediamine crystallises out
6. 6
   温度on cooling

実験手順

122.1 g of a bisazomethine prepared from 2 mols of salicylaldehyde and 1 mol of hexamethylenediamine and having a melting point of 72°-73° C. are hydrogenated in 550 ml of isopropanol in an autoclave in the presence of 8 g of Raney nickel at 75° C. and under a pressure of 90 atmospheres. The product crystallises out at room temperature and is dissolved by boiling with the addition of a further 650 ml of isopropanol. The catalyst is filtered off, and N,N'-bis-(2-hydroxybenzyl)hexamethylenediamine crystallises out on cooling.

出典