反応 #94079

反応方程式

crotonaldehyde

diethyl ketone

sodium methylate

acetic acid

→

2,5,6-trimethyl-2-cyclohexen-1-one

溶媒

methanol

反応条件

後処理

1. 1
   温度under reflux
2. 2
   温度under reflux
3. 3
   その他the mixture obtained
4. 4
   ろ過is filtered
5. 5
   workup.DISTILLATION325 g of diethyl ketone is recovered by distillation of the filtrate

実験手順

70 g of crotonaldehyde is dripped in the course of one hour into a mixture of 400 g of diethyl ketone and 10 g of a 30% solution of sodium methylate in methanol which is boiling under reflux and the reaction mixture is boiled for another half hour under reflux. The whole is neutralized with glacial acetic acid and the mixture obtained is filtered. 325 g of diethyl ketone is recovered by distillation of the filtrate; 55 g of 2,5,6-trimethyl-2-cyclohexen-1-one having a boiling point of from 74° to 76° C. at 12 mm Hg is obtained. The yield with reference to crotonaldehyde is 40%.

出典