反応 #939029

ord-a7fef564d53346fdbb79d60b96c60848

反応方程式

COCCOCCOCCCl
2-chloroethyl 2-(2-methoxyethoxy)ethyl ether
Cc1nc2ccccc2[nH]1
2-methylbenzimidazole
COCCOCCOCCn1c(C)nc2ccccc21
1-[2-[2-(2-Methoxyethoxy)ethoxy]ethyl]-2-methyl-1H-benzimidazole
収率 82.0%

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

1-[2-[2-(2-Methoxyethoxy)ethoxy]ethyl]-2-methyl-1H-benzimidazole was synthesized as in Synthesis Example 1 except that an equimolar amount of 2-methylbenzimidazole was used instead of benzimidazole and an equimolar amount of 2-chloroethyl 2-(2-methoxyethoxy)ethyl ether was used instead of 2-chloroethyl methyl ether. Yield 82%.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US07252925B2uspto-grants-2007_08