反応 #939019

反応方程式

6-decenoic acid

Methyl 6-bromodecanoate

quinoline

methyl 5-decenoate

methyl 6-decenoate

→

5-decenoic acid

収率 35.0%

反応条件

後処理

1. 1
   その他to react at 240° C. for 5 minutes
2. 2
   抽出the reaction solution was extracted with ether
3. 3
   洗浄washed with dilute sulfuric acid
4. 4
   洗浄washed with water
5. 5
   その他dried
6. 6
   その他evaporated
7. 7
   その他to remove the solvent
8. 8
   workup.DISTILLATIONdistilled
9. 9
   その他giving

実験手順

Methyl 6-bromodecanoate (1.2 g) and quinoline (1.2g) were mixed together, and then allowed to react at 240° C. for 5 minutes. After the reaction was completed, the reaction solution was extracted with ether, washed with dilute sulfuric acid, washed with water, dried, evaporated to remove the solvent, and then distilled, thereby giving a mixture of methyl 5-decenoate and methyl 6-decenoate (310 mg). The mixture was hydrolyzed in a coventional manner, thereby giving a mixture (270 mg) of 5-decenoic acid and 6-decenoic acid (1/1).

出典