反応 #939016

反応方程式

sodium

butylmercaptan

ethanol

2-chlorocyclopentane

ethanol

→

2-Butylthiocyclopentanone

反応条件

後処理

1. 1
   その他The ethanol was removed from the mixture
2. 2
   workup.DISSOLUTIONthe residue was dissolved in ether
3. 3
   その他the solvent was evaporated
4. 4
   workup.DISTILLATIONthe resultant was then subjected to distillation
5. 5
   その他giving 2-buthylthiocyclopentanone (90 g)

実験手順

Absolute ethanol (600 ml) was added with metal sodium (13.8 g) and butylmercaptan (64.8 g). A solution of 2-chlorocyclopentane (71.1 g) in absolute ethanol (600 ml) was added to the mixture and then was allowed to stand overnight at a low temperature. The ethanol was removed from the mixture, and the residue was dissolved in ether. The resulting solution was neutralized with aqueous acetic acid solution, the solvent was evaporated, and the resultant was then subjected to distillation, thereby giving 2-buthylthiocyclopentanone (90 g).

出典