反応 #93734

反応方程式

tetrafluoroisophthalonitrile

β-methallyl alcohol

potassium fluoride

→

2,4,5-Trifluoro-6-methallyloxyisopthalonitrile

溶媒

acetonitrile

反応条件

後処理

1. 1
   温度The mixture was cooled
2. 2
   ろ過filtered
3. 3
   その他The filtrate was evaporated under reduced pressure
4. 4
   workup.ADDITIONAfter 50 ml of water was added to the residue
5. 5
   抽出the mixture was extracted with carbon tetrachloride
6. 6
   洗浄washed with water
7. 7
   乾燥dried over sodium sulfate
8. 8
   その他After evaporating carbon tetrachloride
9. 9
   その他the residue of 2.9 g (crystal) was obtained

実験手順

The mixture of 3.0 g of tetrafluoroisophthalonitrile, 1.2 g of β-methallyl alcohol and 1.8 g of potassium fluoride in 30 ml of acetonitrile was stirred at room temperature for 10 hours. The mixture was cooled and filtered. The filtrate was evaporated under reduced pressure. After 50 ml of water was added to the residue, the mixture was extracted with carbon tetrachloride, washed with water, and dried over sodium sulfate. After evaporating carbon tetrachloride, the residue of 2.9 g (crystal) was obtained.

出典