反応 #93549

反応方程式

ε(4-nitro 2-methoxy-benzenesulfonamido)caproic acid

charcoal

→

ε(4-amino 2-methoxy-benzenesulfonamido)caproic acid

収率 98.0%

溶媒

ethyl acetate

反応条件

後処理

1. 1
   その他the hydrogen absorption
2. 2
   その他being terminated
3. 3
   ろ過the catalyst is filtered
4. 4
   濃縮the filtrate concentrated under reduced pressure

実験手順

A solution of ε(4-nitro 2-methoxy-benzenesulfonamido)caproic acid (1.4 g) in solution in ethyl acetate (150 cm3) is stirred magnetically under a hydrogen atmosphere in the presence of 5% palladized charcoal (120 mg). After four hours, the hydrogen absorption being terminated, the catalyst is filtered and the filtrate concentrated under reduced pressure. Pure ε(4-amino 2-methoxy-benzenesulfonamido)caproic acid is obtained, with a yield of 98%.

出典