反応 #92935

反応方程式

1-(4-methylphenyl)-1-oxo-2-bromopropane

1-methylimidazole

→

1-methyl-3-[1-methyl-2-(4-methylphenyl)-2-oxoethyl]-1H-imidazolium bromide

収率 11.0%

溶媒

diethyl ether

反応条件

後処理

1. 1
   その他The reaction solvent was decanted
2. 2
   洗浄the residue was washed with diethyl ether
3. 3
   workup.DISSOLUTIONdissolved in acetonitrile
4. 4
   workup.ADDITIONThe resulting solution was diluted with diethyl ether
5. 5
   ろ過the precipitated solid was collected by filtration
6. 6
   その他The solid was recrystallized from acetonitrile/diethyl ether

実験手順

A solution 2.24 g (0.01 mol) of 1-(4-methylphenyl)-1-oxo-2-bromopropane and 0.9 g (0.011 mol) of 1-methylimidazole in 50 ml of diethyl ether was stirred at room for approximately 18 hours. The reaction solvent was decanted, and the residue was washed with diethyl ether and dissolved in acetonitrile. The resulting solution was diluted with diethyl ether and the precipitated solid was collected by filtration. The solid was recrystallized from acetonitrile/diethyl ether to afford 0.33 g of 1-methyl-3-[1-methyl-2-(4-methylphenyl)-2-oxoethyl]-1H-imidazolium bromide as a solid. (11% yield) mp=175°-177° C.

出典