反応 #92931

反応方程式

α-bromoisobutyrophenone

1-methylimidazole

→

1-methyl-3-(1,1-dimethyl-2-phenyl-2-oxoethyl)-1H-imidazolium bromide

収率 63.0%

溶媒

diethyl ether

反応条件

後処理

1. 1
   その他The solvent was decanted
2. 2
   その他The solvent was again decanted
3. 3
   workup.DISSOLUTIONthe residue was dissolved in acetonitrile
4. 4
   workup.ADDITIONto adding a small portion of ethyl acetate
5. 5
   ろ過A white precipitate was collected by filtration
6. 6
   その他recrystallized from methanol/ethyl acetate

実験手順

A solution of 4.6 g (0.02 mol) of α-bromoisobutyrophenone and 1.8 g (0.022 mol) of 1-methylimidazole in 30 ml of diethyl ether was stirred at room temperature for approximately 48 hours. The solvent was decanted and the resulting oil was slurried in ethyl acetate. The solvent was again decanted and the residue was dissolved in acetonitrile prior to adding a small portion of ethyl acetate. A white precipitate was collected by filtration and recrystallized from methanol/ethyl acetate to afford 3.88 g of 1-methyl-3-(1,1-dimethyl-2-phenyl-2-oxoethyl)-1H-imidazolium bromide as glittering white flakes. (63% yield) mp=137°-140° C.

出典