反応 #9275

反応方程式

2-(1-butynyl)pyridine

O-mesitylenesulfonylhydroxyamine

Diethyl ether

→

N-amino-2-(1-butynyl)pyridinium mesitylenesulfonate

収率 39.1%

溶媒

dichloromethane

dichloromethane

反応条件

後処理

1. 1
   温度while cooling on ice
2. 2
   その他to precipitate crystals, which
3. 3
   ろ過were collected by filtration
4. 4
   その他dried under reduced pressure

実験手順

After dissolving 2-(1-butynyl)pyridine (12.8 g) in dichloromethane (60 mL), a solution of O-mesitylenesulfonylhydroxyamine (Reference document: Synthesis, 1997, 1) (20 g) in dichloromethane (132 mL) was added dropwise while cooling on ice, and the mixture was stirred for 30 minutes. Diethyl ether (2 L) was added to the reaction mixture to precipitate crystals, which were collected by filtration and dried under reduced pressure to obtain N-amino-2-(1-butynyl)pyridinium mesitylenesulfonate (12.6 g) as colorless crystals.

出典