反応 #927225

反応方程式

water

triethylamine

para-acetylaminophenol

lauroyl chloride

→

Lauroyl [4-(N-acetylamino)]phenol

収率 12.0%

溶媒

DMF

反応条件

後処理

1. 1
   その他the product precipitates
2. 2
   洗浄It is washed with heptane
3. 3
   その他dried under vacuum

実験手順

An equivalent amount in moles of para-acetylaminophenol and lauroyl chloride are placed in contact at 0° C. in DMF (dilution=15%) in the presence of one molar equivalent of triethylamine. The mixture is allowed to warm to room temperature with stirring and the reaction medium is then poured into water and the product precipitates. It is washed with heptane and then dried under vacuum. The yield is 12%. The elemental analysis is in accordance with the structure.

出典