反応 #927223

反応方程式

6-hydroxy-2-naphthyl-α-methylacetic acid

acetic anhydride

p-toluenesulfonic acid

→

6-acetoxy-2-naphthyl-α-methylacetic acid

反応条件

後処理

1. 1
   workup.ADDITIONA mixture of 2.2 g
2. 2
   その他The mixture is evaporated
3. 3
   workup.ADDITIONwater is added
4. 4
   抽出the mixture is extracted with diethyl ether which
5. 5
   洗浄is washed with water to neutrality
6. 6
   乾燥dried over sodium sulfate
7. 7
   その他evaporated

実験手順

A mixture of 2.2 g. of 6-hydroxy-2-naphthyl-α-methylacetic acid, 50 ml. of acetic anhydride, and 100 mg. of p-toluenesulfonic acid is stirred for four hours at 50° C. The mixture is evaporated, water is added, and the mixture is extracted with diethyl ether which is washed with water to neutrality, dried over sodium sulfate, and evaporated to yield 6-acetoxy-2-naphthyl-α-methylacetic acid.

出典