反応 #92496

反応方程式

4-(3,4-dichlorophenyl)piperazine

potassium carbonate

2-butanone

→

compound 7p

3-(4-(3,4-dichlorophenyl)piperazine-1-yl)propan-1-ol

反応条件

実験手順

Compound 5 (0.32 mL, 3.54 mmols) was mixed with 4-(3,4-dichlorophenyl)piperazine (0.58 g, 2.5 mmols) and potassium carbonate (0.78 g, 5.6 mmols) in 15 ml 2-butanone overnight at 85° C. as described in General Procedure B to yield compound 7p and was used as is for the next reaction. MS (LC/MS, ESI): 289 (M+H).

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