反応 #9237

反応方程式

1-(6-(3-aminopropanoyl)-2-benzothiazolyl)-3-ethylurea

triethylamine

isocyanate

→

desired compound

収率 25.0%

(6-(3-(3-Methylphenyl)aminocarbonylamino-propanoyl)-2-benzothiazolyl)-3-ethylurea

収率 25.0%

溶媒

DMF

反応条件

後処理

1. 1
   その他Similar to the synthesis of Example 249
2. 2
   その他was reacted

実験手順

Similar to the synthesis of Example 249, a mixture of 1-(6-(3-aminopropanoyl)-2-benzothiazolyl)-3-ethylurea, triethylamine and 3-methylphenhyl isocyanate in DMF was reacted to give the desired compound 0.021 g (25%). LC/MS 426.1 (M+1); LC retention time 2.94 min.

出典