反応 #91956

反応方程式

1-bromo-3,3-dimethyl-butan-2-one

Compound M

4-cyclopropyl-thiazole-2-carboxamidine

→

Compound N

4-tert-Butyl-thiazole-2-carboxamidine

反応条件

実験手順

4-tert-Butyl-thiazole-2-carboxamidine (Compound N) was prepared in analogy to Compound M with procedure shown in Example 10 by using 1-bromo-3,3-dimethyl-butan-2-one instead of 2-bromo-1-cyclopropyl-ethanone. MS: calc'd (MH+) 184, measured (MH+) 184.

出典