反応 #90887

ord-273eca5867b241388ceba11b41776f3b

反応方程式

CC(=O)NC12CC(O)(C1)C2
N-(3-hydroxybicyclo[1.1.1]pentan-1-yl)acetamide
CC(=O)NC12CC(O)(C1)C2
N-(3-hydroxybicyclo[1.1.1]-pentan-1-yl)acetamide
CC(=O)Oc1ccccc1C(=O)Cl
O-acetylsalicyloyl chloride
→
CC(=O)NC12CC(OC(=O)c3ccccc3OC(C)=O)(C1)C2
3-acetamidobicyclo[1.1.1]pentan-1-yl 2-acetoxybenzoate

反応物

CC(=O)NC12CC(O)(C1)C2
N-(3-hydroxybicyclo[1.1.1]pentan-1-yl)acetamide
CC(=O)NC12CC(O)(C1)C2
N-(3-hydroxybicyclo[1.1.1]-pentan-1-yl)acetamide
CC(=O)Oc1ccccc1C(=O)Cl
O-acetylsalicyloyl chloride

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

The general procedure of Example 1 Step 3 is repeated starting with N-(3-hydroxybicyclo[1.1.1]pentan-1-yl)acetamide (1) and using O-acetylsalicyloyl chloride in place of the acetyl chloride to produce 3-acetamidobicyclo[1.1.1]pentan-1-yl 2-acetoxybenzoate (8).

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US09447025B2uspto-grants-2016_09