反応 #90060

ord-4d4cd9bfe4fe432faf2e11f37194625c

反応方程式

COc1cc2c(cc1Br)CCC(=O)C2(C)C
Compound E1
COc1cc2c(cc1Br)CCC(=O)C2(C)C
6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydro-1H-naphthalen-2-one
COc1ccc2c(c1)C(C)(C)c1[nH]c3cc(Br)ccc3c1C2=O
Compound A4
COc1ccc2c(c1)C(C)(C)c1[nH]c3cc(Br)ccc3c1C2=O
3-Bromo-8-methoxy-6,6-dimethyl-5,6-dihydrobenzo[b]carbazol-11-one
→
COc1cc2c(cc1Br)Cc1c([nH]c3cc(Br)ccc13)C2(C)C.COc1cc2c(cc1Br)Cc1c([nH]c3cccc(Br)c13)C2(C)C
title compound
COc1cc2c(cc1Br)Cc1c([nH]c3cc(Br)ccc13)C2(C)C.COc1cc2c(cc1Br)Cc1c([nH]c3cccc(Br)c13)C2(C)C
3,9-Dibromo-8-methoxy-6,6-dimethyl-6,11-dihydro-5H-benzo[b]carbazole 1,9-Dibromo-8-methoxy-6,6-dimethyl-6,11-dihydro-5H-benzo[b]carbazole

反応物

COc1cc2c(cc1Br)CCC(=O)C2(C)C
Compound E1
COc1cc2c(cc1Br)CCC(=O)C2(C)C
6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydro-1H-naphthalen-2-one
COc1ccc2c(c1)C(C)(C)c1[nH]c3cc(Br)ccc3c1C2=O
Compound A4
COc1ccc2c(c1)C(C)(C)c1[nH]c3cc(Br)ccc3c1C2=O
3-Bromo-8-methoxy-6,6-dimethyl-5,6-dihydrobenzo[b]carbazol-11-one

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

Under the same conditions as the method for synthesizing Compound A4, the title compound was prepared (as a mixture) from Compound E1.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US09440922B2uspto-grants-2016_09