反応 #90058

反応方程式

water

7-Methoxy-1,1-dimethyl-3,4-dihydro-1H-naphthalen-2-one

Compound A2

7-Methoxy-1,1-dimethyl-3,4-dihydro-1H-naphthalen-2-one

NBS

→

title compound

収率 92.0%

6-Bromo-7-methoxy-1,1-dimethyl-3,4-dihydro-1H-naphthalen-2-one

収率 92.0%

溶媒

CH3CN

反応条件

後処理

1. 1
   ろ過the precipitated solid was filtered

実験手順

7-Methoxy-1,1-dimethyl-3,4-dihydro-1H-naphthalen-2-one (Compound A2, 2.0 g, 9.791 mmol) was dissolved in CH3CN (40 mL), added with NBS (1.92 g, 1.1 eq.), and the mixture was stirred at room temperature for 2.5 hr. The reaction solution was added to water (40 mL), and the precipitated solid was filtered to obtain the title compound (white powder, 2.55 g, 92%).

出典