反応 #89981

ord-d810174b918b44b8ac9f30d1743b782f

反応方程式

CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
Compound A6
CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
8-Hydroxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
OCCBr
2-bromo-ethanol
→
CC1(C)c2cc(OCCO)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
title compound
CC1(C)c2cc(OCCO)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
8-(2-Hydroxyethoxy)-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

反応物

CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
Compound A6
CC1(C)c2cc(O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21
8-Hydroxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
OCCBr
2-bromo-ethanol

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他Under the same conditions as the method for synthesizing Compound A7-17

実験手順

Under the same conditions as the method for synthesizing Compound A7-17, the title compound was prepared from Compound A6 and 2-bromo-ethanol.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US09440922B2uspto-grants-2016_09