反応 #8757

ord-6c61cccd74a44b228ecf09c6ef86bcb1

反応方程式

BrCCOc1cccc(-c2noc3ccsc23)c1
3-[3-(2-bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole
O=C([O-])[O-].[K+].[K+]
potassium carbonate
Cc1ccc(CN)cc1
4-methylbenzylamine
Cc1ccc(CNCCOc2cccc(-c3noc4ccsc34)c2)cc1
title compound
Cc1ccc(CNCCOc2cccc(-c3noc4ccsc34)c2)cc1
(4-methyl-benzyl)-[2-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-ethyl]-amine

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

The title compound is prepared from 3-[3-(2-bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole, potassium carbonate, 4-methylbenzylamine and acetonitrile essentially as described above in example 18. Purity by LC/MS (APCI)=100%, [M+H]+=365.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US07091199B1uspto-grants-2006_08