反応 #86875

反応方程式

6,6-dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione

3,4-dimethylaniline

→

1-(3,4-dimethylphenyl)-2-oxopyrrolidine-3-carboxylic acid

収率 86.3%

溶媒

ethanol

反応条件

後処理

1. 1
   その他This compound was prepared

実験手順

This compound was prepared according to general method 1 starting from 6,6-dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione (0.250 g; 1.45 mmol) and 3,4-dimethylaniline (0.540 g; 4.36 mmol) in ethanol (3 mL). 1-(3,4-dimethylphenyl)-2-oxopyrrolidine-3-carboxylic acid 0.292 g (86%) was obtained as a white solid.

出典